The vampires, Shake and Mio, have an alliance as improbable as their life spans. Cautious and reclusive, Shake avoids any attention that might compromise his carefully cultivated privacy. His only vampire companion, the wealthy and flamboyant Mio Nagaishi, is, by contrast, indifferent to the dangers of her own extravagance. Shake's only human contact, other than at meal times, is his driver, ex-bartender/ex-hooker, Karla Lambretti. One evening, while taking a woman's blood, Shake finds an envelope containing documents related to the unsolved murder of the woman's husband. Normally, this would be of no interest to Shake. But among the documents is the photo of a man Shake has had his eye on for some time; a wealthy building contractor with connections to the drug trade. On the back of the photo, the woman has written the word, "Bloodsucker". This seemingly innocuous coincidence is the spark that will ignite a blaze that will burn through dirty cops, drug dealers, ex-soviet army thugs, a sentimental private eye, and will finally compel Shake to confront the ghosts of his own past.