Targeted by a mad scientist's deadly serum, these outcasts band together to uncover the truth and to fight back.

Spire City is home to mighty machines of steam power and clockwork, and giant beetles pull picturesque carriages over cobbled streets, but there is a darker secret behind these wonders. A deadly infection, created by a mad scientist, is spreading through the city, targeting the poor and powerless, turning them slowly into animals. A group of those infected by the serum join together to survive, to trick the wealthy out of their money, and to fight back.

After the destruction of the Weave, the former members scatter, thinking only of survival. From the deep catacombs beneath the city to an empty dovecote above one of the city's finest manors, and throughout the streets and storerooms in between, they hide, seek to find what protection they can. As their infections progress, though, they all find that mere protection is not enough. Even in solitude they can work against Orgood, discover what he's doing, and try all they can to stop him, once and for all.

This sequel to Spire City, Season One: Infected and Spire City, Season Two: Pursued includes all thirteen episodes of the third and final season of this steampunk-fantasy series, bringing the story of Chels and the rest to its dramatic conclusion.